Insider Trading disclosures for Rigel Pharmaceuticals

The latest disclosure was made by Raul R. Rodriguez in Rigel Pharmaceuticals where a trade of 26,250 Employee Stock Option (right to buy) done was reported to US exchanges on March 17, 2025.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name	Client Category	Action	Reported to Exchange	Quantity	Post Transaction Holding	Traded %	Avg. Price	Value	Security Type
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	26,250	26,250	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	30,000	30,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	5,625	5,625	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	7,850	7,850	-		-	Employee Stock Option (right to buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	9,375	9,375	-		-	Employee Stock Option (right to buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	7,850	7,850	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	7,850	7,850	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Mar 2025	6,875	6,875	-		-	Employee Stock Option (right to buy)
Mark W. Frohlich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	06 Mar 2025	12,000	12,000	-		-	Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Sale of securities on an exchange or to another person at price $ 20.92 per share.	04 Feb 2025	4,952	243,854 (0%)	0%	20.9	103,601	Common Stock
Raul R. Rodriguez	Director, CEO, President	Sale of securities on an exchange or to another person at price $ 21.93 per share.	04 Feb 2025	4,400	239,454 (0%)	0%	21.9	96,474	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 21.93 per share.	04 Feb 2025	1,734	57,235 (0%)	0%	21.9	38,020	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 20.92 per share.	04 Feb 2025	2,036	58,969 (0%)	0%	20.9	42,595	Common Stock
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Sale of securities on an exchange or to another person at price $ 21.93 per share.	04 Feb 2025	1,339	38,830 (0%)	0%	21.9	29,359	Common Stock
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Sale of securities on an exchange or to another person at price $ 20.92 per share.	04 Feb 2025	1,448	40,169 (0%)	0%	20.9	30,294	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Sale of securities on an exchange or to another person at price $ 21.93 per share.	04 Feb 2025	1,796	51,704 (0%)	0%	21.9	39,379	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Sale of securities on an exchange or to another person at price $ 20.92 per share.	04 Feb 2025	2,125	53,500 (0%)	0%	20.9	44,457	Common Stock
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	63,400	63,400	-		-	Employee Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	42,300	248,806 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	19,717	61,005 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	14,788	14,788	-		-	Employee Stock Option (Right to Buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	14,788	14,788	-		-	Employee Stock Option (Right to Buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	19,717	41,617 (0%)	0%		0	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	19,717	55,625 (0%)	0%		0	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2025	14,788	14,788	-		-	Employee Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.40 per share.	24 Jan 2025	45,000	249,662 (0%)	0%	21.4	963,000	Common Stock
Raul R. Rodriguez	Director, CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.17 per share.	24 Jan 2025	44,078	205,584 (0%)	0%	22.2	977,209	Common Stock
Raul R. Rodriguez	Director, CEO, President	Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.40 per share.	24 Jan 2025	45,000	250,584 (0%)	0%	21.4	963,000	Common Stock
Raul R. Rodriguez	Director, CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.17 per share.	24 Jan 2025	44,078	206,506 (0%)	0%	22.2	977,209	Common Stock
Raul R. Rodriguez	Director, CEO, President	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jan 2025	45,000	0	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jan 2025	45,000	0	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Nov 2024	30,000	30,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Nov 2024	6,250	6,250	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Nov 2024	8,000	8,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Aug 2024	32,500	32,500	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Aug 2024	10,000	10,000	-		-	Employee Stock Option (right to buy)
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	100,000 (0%)	0%		0	Common Stock
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	102,222 (0%)	0%		0	Common Stock
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	100,000 (0%)	0%		0	Common Stock
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	81,250 (0%)	0%		0	Common Stock
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	68,750 (0%)	0%		0	Common Stock
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	30,000	30,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 May 2024	25,000	100,000 (0%)	0%		0	Common Stock
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	300,000	300,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	300,000	300,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	62,500	62,500	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	78,500	78,500	-		-	Employee Stock Option (right to buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	78,500	78,500	-		-	Employee Stock Option (right to buy)
Raymond J. Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	93,750	93,750	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	78,500	78,500	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 Feb 2024	80,000	80,000	-		-	Employee Stock Option (right to buy)
A. David Santos	EVP, Chief Commercial Officer	Sale of securities on an exchange or to another person at price $ 1.14 per share.	02 Feb 2024	8,918	349,093 (0%)	0%	1.1	10,167	Common Stock
A. Santos David	EVP, Chief Commercial Officer	Sale of securities on an exchange or to another person at price $ 1.13 per share.	02 Feb 2024	5,601	358,011 (0%)	0%	1.1	6,329	Common Stock
R. Raul Rodriguez	Director, CEO, President	Sale of securities on an exchange or to another person at price $ 1.13 per share.	02 Feb 2024	22,349	2,067,174 (1%)	0%	1.1	25,261	Common Stock
Raul R. Rodriguez	Director, CEO, President	Sale of securities on an exchange or to another person at price $ 1.14 per share.	02 Feb 2024	30,545	2,036,629 (1%)	0%	1.1	34,821	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 1.13 per share.	02 Feb 2024	5,601	409,918 (0%)	0%	1.1	6,327	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 1.14 per share.	02 Feb 2024	7,027	402,891 (0%)	0%	1.1	8,011	Common Stock
R. Raul Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	400,000	2,089,523 (1%)	0%		0	Common Stock
Rodriguez R. Raul	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	600,000	600,000	-		-	Employee Stock Option (Right to Buy)
J. Raymond Furey	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	209,000	214,000 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	209,000	415,519 (0%)	0%		0	Common Stock
Furey Raymond J.	EVP, GC, CCO & Corp Sec	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	157,000	157,000	-		-	Employee Stock Option (Right to Buy)
A. David Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	209,000	363,612 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	157,000	157,000	-		-	Employee Stock Option (Right to Buy)
David Santos A.	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2024	157,000	157,000	-		-	Employee Stock Option (Right to Buy)
Gary A. Lyons	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	75,000 (0%)	0%		0	Common Stock
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	75,000 (0%)	0%		0	Common Stock
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	77,222 (0%)	0%		0	Common Stock
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	75,000 (0%)	0%		0	Common Stock
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	56,250 (0%)	0%		0	Common Stock
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	43,750 (0%)	0%		0	Common Stock
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	30,000	30,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2023	25,000	75,000 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 1.66 per share.	02 Feb 2023	5,389	196,519 (0%)	0%	1.7	8,946	Common Stock
Wolfgang Dummer	EVP & CMO	Sale of securities on an exchange or to another person at price $ 1.66 per share.	02 Feb 2023	5,389	72,459 (0%)	0%	1.7	8,946	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Sale of securities on an exchange or to another person at price $ 1.66 per share.	02 Feb 2023	5,388	144,612 (0%)	0%	1.7	8,945	Common Stock
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	300,000	1,701,053 (1%)	0%		0	Common Stock
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	200,000	400,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	600,000	600,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Sale of securities on an exchange or to another person at price $ 1.75 per share.	26 Jan 2023	20,340	1,680,713 (0%)	0%	1.8	35,595	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	50,000	100,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	63,000	201,908 (0%)	0%		0	Common Stock
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	125,000	125,000	-		-	Employee Stock Option (right to buy)
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	50,000	100,000	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	160,000	160,000	-		-	Employee Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	80,000	150,000 (0%)	0%		0	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	50,000	100,000	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Sep 2022	81,250	81,250	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Sep 2022	300,000	300,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Sep 2022	81,250	81,250	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Purchase of securities on an exchange or from another person at price $ 0.69 per share.	09 Jun 2022	1,000,000	1,391,776 (0%)	0%	0.7	688,400	Common Stock
Gary A. Lyons	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	50,000 (0%)	0%		0	Common Stock
Gary A. Lyons	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	50,000 (0%)	0%		0	Common Stock
Jane Wasman	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	52,222 (0%)	0%		0	Common Stock
Walter H. Moos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	50,000 (0%)	0%		0	Common Stock
Gregg Anthony Lapointe	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	31,250 (0%)	0%		0	Common Stock
Alison L. Hannah	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	18,750	18,750 (0%)	0%		0	Common Stock
Kamil Ali-Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	22,500	22,500	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	25,000	50,000 (0%)	0%		0	Common Stock
Brian L. Kotzin	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2022	30,000	30,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	50,000	60,260 (0%)	0%		0	Common Stock
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	100,000	100,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	400,000	400,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	200,000	391,776 (0%)	0%		0	Common Stock
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	50,000	128,908 (0%)	0%		0	Common Stock
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	100,000	100,000	-		-	Stock Option (Right to Buy)
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	50,000	67,848 (0%)	0%		0	Common Stock
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	100,000	100,000	-		-	Stock Option (Right to Buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	50,000	60,000 (0%)	0%		0	Common Stock
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2022	100,000	100,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	125,000	125,000	-		-	Stock Option(right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	525,000	525,000	-		-	Stock Option(right to buy)
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	112,500	112,500	-		-	Stock Option(right to buy)
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	125,000	125,000	-		-	Stock Option(right to buy)
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	37,500	37,500	-		-	Stock Option (right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Jan 2021	137,500	137,500	-		-	Stock Option(right to buy)
David A. Santos	EVP, Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Aug 2020	250,000	250,000	-		-	Employee Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Jane Wasman	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 May 2020	55,000	55,000	-		-	Stock Option (Right to Buy)
Nelson Cabatuan	VP,Finance & Princ.Acctg. Off.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	20,000	20,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	06 Feb 2020	150,000	150,000	-		-	Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	06 Feb 2020	650,000	650,000	-		-	Stock Option (right to buy)
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	06 Feb 2020	200,000	200,000	-		-	Stock Option (right to buy)
Nelson Cabatuan	VP,Finance & Princ.Acctg. Off.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	06 Feb 2020	90,000	90,000	-		-	Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	75,000	75,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	237,500	237,500	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	83,750	83,750	-		-	Employee Stock Option (right to buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	75,000	75,000	-		-	Employee Stock Option (right to buy)
Joseph Lasaga	Sr.VP Bus.Dev.Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	43,750	43,750	-		-	Employee Stock Option (right to buy)
Esteban Masuda	Sr. VP Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	18 Nov 2019	62,500	62,500	-		-	Employee Stock Option (right to buy)
Wolfgang Dummer	EVP & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Nov 2019	220,000	220,000	-		-	Employee Stock Option (right to buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Jane Wasman	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	13,750	13,750	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2019	55,000	55,000	-		-	Stock Option (Right to Buy)
Dean Schorno	EVP &Chief Financial Officer	Purchase of securities on an exchange or from another person at price $ 2.13 per share.	22 May 2019	3,274	50,000 (0%)	0%	2.1	6,971	Common Stock
Dean Schorno	EVP &Chief Financial Officer	Purchase of securities on an exchange or from another person at price $ 2.13 per share.	22 May 2019	46,726	46,726 (0%)	0%	2.1	99,573	Common Stock
Jane Wasman	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Apr 2019	80,000	80,000	-		-	Stock Option ( Right to Buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	75,000	75,000	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	75,000	75,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	237,500	237,500	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	83,750	83,750	-		-	Employee Stock Option (right to buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	75,000	75,000	-		-	Employee Stock Option (right to buy)
Joseph Lasaga	Sr.VP Bus.Dev.Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	43,750	43,750	-		-	Employee Stock Option (right to buy)
Esteban Masuda	Sr. VP Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	62,500	62,500	-		-	Employee Stock Option (right to buy)
Stacy Markel	EVP Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Mar 2019	62,500	62,500	-		-	Employee Stock Option (right to buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	162,500	162,500	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	162,500	162,500	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	600,000	600,000	-		-	Employee Stock Option (right to buy)
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	162,500	162,500	-		-	Employee Stock Option (right to buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	200,000	200,000	-		-	Employee Stock Option (right to buy)
Joseph Lasaga	Sr.VP Bus.Dev.Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	100,000	100,000	-		-	Employee Stock Option (right to buy)
Esteban Masuda	Sr. VP Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	100,000	100,000	-		-	Employee Stock Option (right to buy)
Nelson Cabatuan	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	60,000	60,000	-		-	Employee Stock Option (right to buy)
Stacy Markel	EVP Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Jan 2019	137,500	137,500	-		-	Employee Stock Option (right to buy)
Nelson Cabatuan	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 3.12 per share.	12 Oct 2018	10,000	58 (0%)	0%	3.1	31,200	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 3.50 per share.	17 Sep 2018	37,500	0 (0%)	0%	3.5	131,250	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.11 per share.	17 Sep 2018	37,500	37,500 (0%)	0%	2.1	79,125	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 3.50 per share.	17 Sep 2018	115,500	0 (0%)	0%	3.5	404,250	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.54 per share.	17 Sep 2018	115,500	115,500 (0%)	0%	2.5	293,370	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	17 Sep 2018	115,500	268,000	-		-	Employe Stock Option (right to buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	17 Sep 2018	37,500	112,500	-		-	Employee Stock Option (right to buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Purchase of securities on an exchange or from another person at price $ 3.28 per share.	10 Sep 2018	50,000	165,000 (0%)	0%	3.3	164,210	Common Stock
Eldon C. Mayer	EVP & Chief Commercial Officer	Purchase of securities on an exchange or from another person at price $ 3.23 per share.	10 Sep 2018	50,000	215,000 (0%)	0%	3.2	161,340	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Sep 2018	16,500	383,500	-		-	Employe Stock Option (right to buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 3.51 per share.	04 Sep 2018	16,500	0 (0%)	0%	3.5	57,861	Common Stock
Anne-Marie Duliege	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.54 per share.	04 Sep 2018	16,500	16,500 (0%)	0%	2.5	41,910	Common Stock
Eldon C. Mayer	EVP & Chief Commercial Officer	Purchase of securities on an exchange or from another person at price $ 2.82 per share.	23 Aug 2018	100,000	115,000 (0%)	0%	2.8	282,320	Common Stock
Raul R. Rodriguez	Director, CEO, President	Purchase of securities on an exchange or from another person at price $ 2.63 per share.	17 Aug 2018	114,000	173,519 (0%)	0%	2.6	300,002	Common Stock
Nelson Cabatuan	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Aug 2018	20,000	20,000	-		-	Employee Stock Option (Right to Buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 2.79 per share.	02 Jul 2018	5,000	0 (0%)	0%	2.8	13,932	Common Stock
Dean Schorno	EVP &Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Jun 2018	167,500	167,500	-		-	Employee Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Gregg Anthony Lapointe	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	30,000	30,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	40,000	40,000	-		-	Stock Option (Right to Buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	150,000	150,000	-		-	Employee Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	150,000	150,000	-		-	Employee Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	450,000	450,000	-		-	Employee Stock Option (Right to Buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	50,000	50,000	-		-	Employee Stock Option (Right to Buy)
Joseph Lasaga	VP Bus. Dev.& Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	25,000	25,000	-		-	Employee Stock Option (Right to Buy)
Esteban Masuda	Sr. VP Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 May 2018	50,000	50,000	-		-	Employee Stock Option (Right to Buy)
Anne-Marie Duliege	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 4.11 per share.	20 Apr 2018	5,000	0 (0%)	0%	4.1	20,550	Common Stock
Stacy Markel	EVP Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Mar 2018	125,000	125,000	-		-	Employee Stock Option (Right to Buy)
Anne-Marie Duliege	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	150,000	150,000	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	150,000	150,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	475,000	475,000	-		-	Employee Stock Option (right to buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	150,000	150,000	-		-	Employee Stock Option (right to buy)
Joseph Lasaga	VP Bus. Dev.& Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	87,500	87,500	-		-	Employee Stock Option (right to buy)
Esteban Masuda	Sr. VP Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	125,000	125,000	-		-	Employee Stock Option (right to buy)
Nelson Cabatuan	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2018	24,000	24,000	-		-	Employee Stock Option (right to buy)
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Nov 2017	100,000	75,000	-		-	Employee Stock Option (right to buy)
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 3.90 per share.	03 Nov 2017	100,000	0 (0%)	0%	3.9	390,000	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.14 per share.	03 Nov 2017	100,000	100,000 (0%)	0%	2.1	214,000	Common Stock
Gregg Anthony Lapointe	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Oct 2017	80,000	80,000	-		-	Stock Option (Right to Buy)
Brian L. Kotzin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Aug 2017	80,000	80,000	-		-	Stock Option (Right to Buy)
Anne-Marie Duliege	Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 2.69 per share.	05 Jul 2017	5,000	0 (0%)	0%	2.7	13,427	Common Stock
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 May 2017	40,000	40,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 May 2017	40,000	40,000	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 May 2017	40,000	40,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 May 2017	40,000	40,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 May 2017	40,000	40,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	62,500	62,500	-		-	Employee Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	150,000	150,000	-		-	Employee Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	400,000	400,000	-		-	Employee Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	75,000	75,000	-		-	Employee Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	150,000	150,000	-		-	Employee Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Apr 2017	62,500	62,500	-		-	Employee Stock Option (Right to Buy)
Anne-Marie Duliege	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	150,000	150,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	150,000	150,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	450,000	450,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	150,000	150,000	-		-	Stock Option (Right to Buy)
Eldon C. Mayer	EVP & Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	50,000	50,000	-		-	Stock Option (Right to Buy)
Joseph Lasaga	VP Bus. Dev.& Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	25,000	25,000	-		-	Stock Option (Right to Buy)
Esteban Masuda	Sr. VP Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2017	50,000	50,000	-		-	Stock Option (Right to Buy)
Anne-Marie Duliege	Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 2.41 per share.	03 Jan 2017	5,000	0 (0%)	0%	2.4	12,028	Common Stock
Eldon C. Mayer	EVP &Chief Commercial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	10 Oct 2016	300,000	300,000	-		-	Employee Stock Option (Right to Buy)
Joseph Lasaga	VP Bus. Dev.& Alliance Mgmt.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	10 Oct 2016	150,000	150,000	-		-	Employee Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	30 Aug 2016	5,303	53,031	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 May 2016	40,000	40,000	-		-	Stock Option (Right to Buy)
Anne-Marie Duliege	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	05 May 2016	400,000	400,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	175,000	175,000	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	62,500	62,500	-		-	Employee Stock Option (right to buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	200,000	200,000	-		-	Employee Stock Option (right to buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	75,000	75,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	75,000	75,000	-		-	Employee Stock Option (right to buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	450,000	450,000	-		-	Employee Stock Option (right to buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	62,500	62,500	-		-	Employee Stock Option (right to buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Apr 2016	175,000	175,000	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2016	150,000	150,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2016	165,000	165,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2016	150,000	150,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2016	400,000	400,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2016	150,000	150,000	-		-	Stock Option (Right to Buy)
Keith A. Katkin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jun 2015	80,000	80,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	10 Jun 2015	41,666	58,334	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Jun 2015	41,666	100,000	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Jun 2015	41,666	158,334	-		-	Stock Option (Right to Buy)
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2015	40,000	40,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2015	40,000	40,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2015	40,000	40,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2015	40,000	40,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2015	40,000	40,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	01 Apr 2015	10,000	58,334	-		-	Common Stock
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2015	175,000	175,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2015	200,000	200,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2015	175,000	175,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	Director, CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2015	450,000	450,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2015	175,000	175,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Sale of securities on an exchange or to another person at price $ 0.00 per share.	18 Dec 2014	1,000	575	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	03 Sep 2014	20,000	68,334	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2014	30,000	30,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2014	30,000	30,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2014	30,000	30,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2014	30,000	30,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2014	30,000	30,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	125,000	125,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	150,000	150,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	150,000	150,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	250,000	250,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	President & COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	150,000	150,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Feb 2014	125,000	125,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	24 Feb 2014	20,000	88,334	-		-	Common Stock
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	150,000	150,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	200,000	200,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	150,000	150,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	225,000	225,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	President & COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	150,000	150,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Jan 2013	150,000	150,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Sale of securities on an exchange or to another person at price $ 0.00 per share.	13 Sep 2012	4,151	1,103	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Sep 2012	23,302	73,300	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Sep 2012	23,302	23,302	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	12 Sep 2012	23,302	0	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Sep 2012	34,112	34,112	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Sep 2012	34,112	0	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Sep 2012	17,586	17,586	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Sep 2012	17,586	0	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Sep 2012	34,112	114,188	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Sep 2012	17,586	96,602	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Aug 2012	1,700	1,700	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Aug 2012	700	1,000	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Aug 2012	100	900	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Aug 2012	600	300	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Sale of securities on an exchange or to another person at price $ 0.00 per share.	07 Aug 2012	300	0	-		-	Common Stock
Ryan D. Maynard	EVP & CFO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Aug 2012	1,700	148,300	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jun 2012	100	118,234	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jun 2012	100	118,134	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jun 2012	9,700	108,434	-		-	Common Stock
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jun 2012	100	108,334	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2012	15,000	15,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	150,000	150,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	200,000	200,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	150,000	150,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	225,000	225,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	President & COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	150,000	150,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2012	150,000	150,000	-		-	Stock Option (Right to Buy)
Flynn E James	Other	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	26 May 2011	46,524	470,425	-		-	Common Stock
Flynn E James	Other	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	26 May 2011	72,800	762,700	-		-	Common Stock
Flynn E James	Other	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	26 May 2011	229,252	2,279,997	-		-	Common Stock
Flynn E James	Other	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	26 May 2011	301,424	3,204,167	-		-	Common Stock
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2011	15,000	15,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2011	15,000	15,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 May 2011	15,000	15,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	President & COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Feb 2011	65,000	65,000	-		-	Stock Option (Right to Buy)
Flynn E James	Other	Sale of securities on an exchange or to another person at price $ 0.00 per share.	03 Nov 2010	2,605	2,050,745	-		-	Common Stock
Flynn E James	Other	Sale of securities on an exchange or to another person at price $ 0.00 per share.	03 Nov 2010	3,690	2,902,743	-		-	Common Stock
Flynn E James	Other	Sale of securities on an exchange or to another person at price $ 0.00 per share.	03 Nov 2010	516	423,901	-		-	Common Stock
Flynn E James	Other	Sale of securities on an exchange or to another person at price $ 0.00 per share.	03 Nov 2010	900	689,900	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	28 May 2010	15,000	15,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	EVP Corp. Affairs, G.C., Sect.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 May 2010	67,000	67,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	President & COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 May 2010	175,000	175,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	EVP & CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 May 2010	120,000	120,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	SVP, Gen. Counsel, Corp. Sec.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	105,000	105,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	165,000	165,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	115,000	115,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	220,000	220,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	125,000	125,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	VP, CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2010	85,000	85,000	-		-	Stock Option (Right to Buy)
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2009	10,000	10,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	SVP, Gen. Counsel, Corp. Sec.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	100,000	100,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	145,000	145,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	115,000	115,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	190,000	190,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	115,000	115,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	VP, CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 Mar 2009	150,000	150,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Jan 2009	3,334	0	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Jan 2009	3,334	118,334	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	SVP, Gen. Counsel, Corp. Sec.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	90,000	90,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, EVP, Pres. Discovery&Research	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	140,000	140,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	EVP, CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	130,000	130,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	165,000	165,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	125,000	125,000	-		-	Stock Option (Right to Buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	10,000	10,000	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	VP, CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2008	75,000	75,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	300	300	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	100	400	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	600	1,000	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	800	1,800	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	1,385	3,185	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	1,815	5,000	-		-	Common Stock
Bradford S. Goodwin	None	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	09 Aug 2007	5,000	10,000	-		-	Common Stock
Walter H. Moos	None	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jun 2007	2,222	0	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jun 2007	2,222	2,222	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jun 2007	10,000	10,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	Sr. VP Medical Development	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	29 May 2007	2,000	2,000	-		-	Common Stock
Dolly A. Vance	SVP, Gen. Counsel, Corp. Sec.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	103,788	103,788	-		-	Stock Option (right to buy)
Donald G. Payan	Director, Ex. VP Chief Sci. Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	80,000	80,000	-		-	Stock Option (right to buy)
Elliott B. Grossbard	Sr. VP Medical Development	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	80,000	80,000	-		-	Stock Option (right to buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	100,000	100,000	-		-	Stock Option (right to buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	80,000	80,000	-		-	Stock Option (right to buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	20,000	20,000	-		-	Stock Option (right to buy)
Ryan D. Maynard	VP, CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2007	106,911	106,911	-		-	Stock Option (right to buy)
Bradford S. Goodwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	24 Jan 2007	20,000	20,000	-		-	Stock Option (Right to Buy)
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	4,039	4,039	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	1,112	1,112	-		-	Stock Option (Right to Buy)
Alan D. Frazier	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	556	556	-		-	Stock Option (Right to Buy)
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	16,249	16,249	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	Sr. VP Medical Development	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	27,778	27,778	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	43,889	43,889	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	1,112	1,112	-		-	Stock Option (Right to Buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	1,111	1,111	-		-	Stock Option (Right to Buy)
Ryan D. Maynard	VP Finance, Acting CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Aug 2006	1,000	1,000	-		-	Stock Option (Right to Buy)
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Alan D. Frazier	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 May 2006	10,000	10,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	45,000	45,000	-		-	Stock Option (right to buy)
Donald G. Payan	Director, Ex. VP Chief Sci. Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	55,000	55,000	-		-	Stock Option (right to buy)
Elliott B. Grossbard	Sr. VP Medical Development	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	60,000	60,000	-		-	Stock Option (right to buy)
James H. Welch	CFO, VP & Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	45,000	45,000	-		-	Stock Option (right to buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	60,000	60,000	-		-	Stock Option (right to buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	65,000	65,000	-		-	Stock Option (right to buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	25 Jan 2006	20,000	20,000	-		-	Stock Option (right to buy)
Alan D. Frazier	None	Gift of securities by or to the insider at price $ 0.00 per share.	31 Dec 2005	10,905	0	-		-	Common Stock
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	07 Dec 2005	1,000	9,000	-		-	Common Stock
Jean Deleage	None	Other type of transaction at price $ 0.00 per share.	02 Nov 2005	315,423	0	-		-	Common Stock
Jean Deleage	None	Other type of transaction at price $ 0.00 per share.	02 Nov 2005	11,604	0	-		-	Common Stock
Jean Deleage	None	Other type of transaction at price $ 0.00 per share.	02 Nov 2005	697	697	-		-	Common Stock
James M. Gower	Director, CEO & Board Chairman	Other type of transaction at price $ 0.00 per share.	02 Nov 2005	297	126,736	-		-	Common Stock
James M. Gower	Director, CEO & Board Chairman	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2005	50,000	180,676	-		-	Common Stock
James M. Gower	Director, CEO & Board Chairman	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2005	50,000	0	-		-	Stock Option (Right to Buy)
Gary A. Lyons	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	05 Oct 2005	20,000	20,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	80,000	80,000	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, Ex. VP Chief Sci. Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	93,000	93,000	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	Sr. VP Medical Development	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	65,000	65,000	-		-	Stock Option (Right to Buy)
James H. Welch	CFO, VP & Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	90,000	90,000	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	200,000	200,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	55,000	55,000	-		-	Stock Option (Right to Buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	04 Oct 2005	40,000	40,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	26 Jul 2005	122,684	358,633	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	26 Jul 2005	4,513	13,194	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	26 Jul 2005	43,210	315,423	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	26 Jul 2005	1,590	11,604	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	25 Jul 2005	6,173	481,317	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	25 Jul 2005	227	17,707	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	21 Jul 2005	565	487,490	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	21 Jul 2005	21	17,934	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jul 2005	34,153	596,692	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jul 2005	1,256	21,952	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jul 2005	108,637	488,055	-		-	Common Stock
Jean Deleage	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	19 Jul 2005	3,997	17,955	-		-	Common Stock
Stephen A. Sherwin	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Hollings C. Renton	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Nicholas J. Simon	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Jean Deleage	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Alan D. Frazier	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Walter H. Moos	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jun 2005	10,000	10,000	-		-	Stock Option (Right to Buy)
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 May 2005	15,000	19,385	-		-	Common Stock
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Sale of securities on an exchange or to another person at price $ 0.00 per share.	10 May 2005	15,000	4,385	-		-	Common Stock
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 May 2005	15,000	16,249	-		-	Employee Stock Option (right to buy)
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	30 Mar 2005	1,000	4,385	-		-	Common Stock
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	08 Feb 2005	200	7,700	-		-	Common Stock
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Purchase of securities on an exchange or from another person at price $ 0.00 per share.	08 Feb 2005	300	8,000	-		-	Common Stock
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2005	13,333	13,333	-		-	Stock Option (Right to Buy)
Peter S. Ringrose	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Feb 2005	6,667	6,667	-		-	Stock Option (Right to Buy)
Alan D. Frazier	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	24 Jan 2005	2,332	0	-		-	Common Stock
Alan D. Frazier	None	Other type of transaction at price $ 0.00 per share.	24 Jan 2005	459,563	0	-		-	Common Stock
Alan D. Frazier	None	Other type of transaction at price $ 0.00 per share.	24 Jan 2005	481,396	0	-		-	Common Stock
Alan D. Frazier	None	Other type of transaction at price $ 0.00 per share.	24 Jan 2005	4,917	10,905	-		-	Common Stock
Dolly A. Vance	VP Intel. Prop.& Gen.Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	38,751	38,751	-		-	Stock Option (Right to Buy)
Donald G. Payan	Director, Ex. VP Chief Sci. Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	11,250	11,250	-		-	Stock Option (Right to Buy)
Elliott B. Grossbard	Sr. VP Medical Development	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	32,222	32,222	-		-	Stock Option (Right to Buy)
James H. Welch	CFO, VP & Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	27,777	27,777	-		-	Stock Option (Right to Buy)
James M. Gower	Director, CEO & Board Chairman	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	15,000	15,000	-		-	Stock Option (Right to Buy)
Raul R. Rodriguez	EVP, COO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	12,500	12,500	-		-	Stock Option (Right to Buy)
Robin D.G. Cooper	Sr. V.P. Pharmaceutical Scs.	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2005	2,500	2,500	-		-	Stock Option (Right to Buy)
Dennis Henner	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	05 Jan 2005	1,700	1,715	-		-	Common Stock
Dennis Henner	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	05 Jan 2005	200	1,515	-		-	Common Stock
Dennis Henner	None	Sale of securities on an exchange or to another person at price $ 0.00 per share.	05 Jan 2005	100	1,415	-		-	Common Stock

*All Values are in $ Million

Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc
Security Type: Share/ Warrants / Convertible Debentures

Data as reported to USA Exchanges

View All The Insider Trades disclosures

31.69% Fall from 52W High

Insider Trading disclosures for Rigel Pharmaceuticals

The latest disclosure was made by Raul R. Rodriguez in Rigel Pharmaceuticals where a trade of 26,250 Employee Stock Option (right to buy) done was reported to US exchanges on March 17, 2025.

Screeners based on Insider Trading and SAST parameters